PLMS is a Comprehensive Pathology Laboratory Management Software. This Software efficiently manages patient reports, commercial records and the administrative activities of a pathology laboratory. Apart from the standard features of other laboratory management software, PLMS was developed considering the end user in mind. The easy navigation enables users to obtain information at their finger tips. PLMS is seamlessly integrated software catering to all types of users in a lab. The use of hot keys and function keys boosts the speed of data entry considerably.